Food Cooked at High Temperature May Increase Alzheimer's Risk

According to a study published in the Journal of Alzheimer's Disease, eating food cooked at high temperature increases the risk of Alzheimer's Disease.

When a food is cooked at high temperatures; the content of advanced glycation end products (AGEs) increases.

(AGEs) are a group of compounds that are combinations of sugars, proteins and other large molecules. AGEs increase the risk of various chronic diseases including increased inflammation and oxidative stress. They can also combine to the receptor for AGEs (RAGE). RAGE transports beta-amyloid proteins across the blood-brain barrier and contributes to the development of Alzheimer's disease, the researchers explained. 

The researchers found that the higher the cooking temperature, the higher the AGEs content in food. Meat made the highest contribution of AGEs, followed by vegetable oils, cheese and fish. The diet containing larger quantities of AGEs were correlated with higher incidence of Alzheimer's Disease. The study was conducted by researchers at the Mount Sinai School of Medicine in New York. 

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Alzheimer’s Disease in India: Awareness

Alzheimer’s Disease (AD) is an illness in which the mental ability of persons gradually declines and brain stops to function in a normal way; is the most common type of dementia. It adversely affects memory, thought process, and behavioral mannerism. It is generally seen in elderly people. It’s more harmful for people over 55.

Symptoms of Alzheimer’s Disease usually develops slowly, and gradually worsen over time. It starts with minor forgetfulness and transmutes into a serious mental disorder. At an advanced stage of AD, it becomes difficult for the person to lead a normal life. Patients can’t even identify the people close to them. They lose both visual and verbal memories. They forget recent conversations, names of recent acquaintances, misplace objects, and lose way in familiar surroundings. The progression rate of this disease is different for everyone. However, people with Alzheimer’s live for around eight years after symptoms begin.  

Short-term memory loss is very common symptom of the people suffering from AD. 

Currently, there are no cures for Alzheimer’s Disease. Many countries have day care centers for such patients. But in India, the family is the care-giver. 

Globally, one out of 10 persons who are above 80 years and one out of four persons who are above 90 years suffer from Alzheimer’s. In India, we have nearly 50 lakh dementia patients, of which around 70 to 80 % have Alzheimer’s.

Associate professor, Department of Neurology, NIMS, Dr. K. Rukmini Mridula says, “AD occurs due to abnormal and toxic protein accumulation in neurons. We lose the capacity to remove toxic proteins with age and that’s why such ailments manifest in older age”. AD is the most common neuro-degenerative disease.

Common symptoms of Alzheimer’s Disease (AD):

• Problem in completing tasks that were once easy to do
• Complexity in planning and difficulty in solving problems
• Frequent mood swings or changes in personality
• Problems with communication
• Confusion about places, people, and events
• Trouble in understanding images
• Schizophonic thoughts

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